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Therapy Name SGN-35T
Synonyms
Therapy Description

SGN-35T is an antibody-drug conjugate (ADC) comprising an anti-TNFRSF8 (CD30) antibody conjugated to monomethyl auristatin E (MMAE), which potentially induces cell cycle arrest and inhibits tumor growth (Mol Cancer Ther (2023) 22 (12_Supplement): C132).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SGN-35T SGN-35T is an antibody-drug conjugate (ADC) comprising an anti-TNFRSF8 (CD30) antibody conjugated to monomethyl auristatin E (MMAE), which potentially induces cell cycle arrest and inhibits tumor growth (Mol Cancer Ther (2023) 22 (12_Supplement): C132).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06120504 Phase I SGN-35T A Safety Study of SGN-35T in Adults With Advanced Cancers Recruiting USA | GBR | ESP | DNK | CAN 0


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