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Therapy Name | SGN-35T |
Synonyms | |
Therapy Description |
SGN-35T is an antibody-drug conjugate (ADC) comprising an anti-TNFRSF8 (CD30) antibody conjugated to monomethyl auristatin E (MMAE) via a D-leucine-alanine-glutamate linker, which potentially induces cell cycle arrest and inhibits tumor growth (Mol Cancer Ther (2023) 22 (12_Supplement): C132). |