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Therapy Name M5A-IL2
Synonyms
Therapy Description

M5A-IL2 ICK comprises an anti-CEA antibody fused to human IL-2, which potentially induces an immune response against tumor cells expressing CEA, resulting in tumor growth inhibition (PMID: 32117587).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
M5A-IL2 M5A-ICK|M5A-IL2 immunocytokine|M5A-IL-2 CEACAM5 Antibody 8 M5A-IL2 is an immunocytokine comprising an anti-CEA antibody fused to human IL-2, which potentially induces an immune response against tumor cells expressing CEA, resulting in tumor growth inhibition (PMID: 32117587).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06130826 Phase I M5A-IL2 Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer Recruiting USA 0


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