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Therapy Name BH3120
Synonyms
Therapy Description

BH3120 is a bispecific antibody targeting CD274 (PD-L1) and TNFRSF9 (4-1BB), which potentially induces antitumor immune activity (Cancer Res (2023) 83 (7_Supplement): 1799).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
BH3120 BH-3120|BH 3120 PD-L1/PD-1 antibody 122 TNFRSF9 Antibody 32 BH3120 is a bispecific antibody targeting CD274 (PD-L1) and TNFRSF9 (4-1BB), which potentially induces antitumor immune activity (Cancer Res (2023) 83 (7_Supplement): 1799).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06234397 Phase I BH3120 Dose Escalation and Expansion Study of BH3120 in Advanced or Metastatic Solid Tumors Recruiting USA 1


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