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| Therapy Name | FT825 |
| Synonyms | |
| Therapy Description |
FT825 is a chimeric antigen receptor (CAR) T cell therapy targeting ERBB2 (HER2), which potentially decreases growth of ERBB2 (HER2)-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11). |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| FT825 | FT-825|FT 825|ONO-8250|ONO 8250|ONO8250 | HER2 (ERBB2) Immune Cell Therapy 9 | FT825 is a chimeric antigen receptor (CAR) T cell therapy targeting ERBB2 (HER2), which potentially decreases growth of ERBB2 (HER2)-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06241456 | Phase I | Cetuximab + FT825 Bendamustine + Cisplatin + Docetaxel FT825 Cyclophosphamide + Fludarabine | FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors | Recruiting | USA | 0 |