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Therapy Name CART-EGFR-IL13Ra2 cells
Synonyms
Therapy Description

CART-EGFR-IL13Ra2 cells are autologous T-lymphocytes engineered to express chimeric antigen receptors (CARs) that target EGFR epitope 806 and IL13Ra2, which potentially induce toxicity in tumor cells expressing EGFR or IL13Ra2 (PMID: 40451950, NCI Drug Dictionary).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
CART-EGFR-IL13Ra2 cells IL13RA2 Immune Cell Therapy 7 CART-EGFR-IL13Ra2 cells are autologous T-lymphocytes engineered to express chimeric antigen receptors (CARs) that target EGFR epitope 806 and IL13Ra2, which potentially induce toxicity in tumor cells expressing EGFR or IL13Ra2 (PMID: 40451950, NCI Drug Dictionary).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06973096 Phase I CART-EGFR-IL13Ra2 cells CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy Recruiting USA 0
NCT07209241 Phase I CART-EGFR-IL13Ra2 cells Different Approaches for CART-EGFR-IL13Ra2 Dosing in Recurrent GBM Recruiting USA 0
NCT05168423 Phase I CART-EGFR-IL13Ra2 cells CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM Active, not recruiting USA 0


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