Therapy Detail
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| Therapy Name | C7R.CD30.CAR-EBVS T-cells |
| Synonyms | |
| Therapy Description |
C7R.CD30.CAR-EBVS T-cells are allogeneic Epstein Barr virus-specific T-cells (EBVSTs) engineered to express a chimeric antigen receptor (CAR) recognizing CD30, IL7R, and an inducible caspase 9 (iC9), which potentially inhibits tumor growth (NCI Thesaurus). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| C7R.CD30.CAR-EBVS T-cells | C7R.CD30.CAR-EBVST cells | CD30 (TNFRSF8) Immune Cell Therapy 5 | C7R.CD30.CAR-EBVS T-cells are allogeneic Epstein Barr virus-specific T-cells (EBVSTs) engineered to express a chimeric antigen receptor (CAR) recognizing CD30, IL7R, and an inducible caspase 9 (iC9), which potentially inhibits tumor growth (NCI Thesaurus). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06176690 | Phase I | C7R.CD30.CAR-EBVS T-cells | Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas (CABAL2) | Recruiting | USA | 0 |
| NCT07729397 | Phase I | C7R.CD30.CAR-EBVS T-cells | Autologous IC-Nine, CD30 CAR, and Constitutive IL7R Expressing EBVST for CD30 Lymphoma (ANCILE-30) (ANCILE-30) | Not yet recruiting | USA | 0 |
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