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Therapy Detail
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| Therapy Name | SCG101 |
| Synonyms | |
| Therapy Description |
SCG101 comprises CD4- and CD8-positive autologous T-lymphocytes engineered to express a T-cell receptor targeting HBsAg, which potentially induce cytotoxicity against tumor cells and enhance antitumor immune activity (Journal for ImmunoTherapy of Cancer 2022;10). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| SCG101 | SCG-101|SCG 101 | SCG101 comprises CD4- and CD8-positive autologous T-lymphocytes engineered to express a T-cell receptor targeting HBsAg, which potentially induce cytotoxicity against tumor cells and enhance antitumor immune activity (Journal for ImmunoTherapy of Cancer 2022;10). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05417932 | Phase Ib/II | SCG101 | A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma | Recruiting | USA | 2 |
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