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| Therapy Name | TMV vaccine |
| Synonyms | |
| Therapy Description |
TMV vaccine is a personalized cancer vaccine comprising tumor-derived membrane vesicles containing immunostimulatory molecules, which potentially induces an antitumor immune response and inhibits tumor growth (PMID: 32295135). |
| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TMV vaccine | Tumor membrane vesicle vaccine | TMV vaccine is a personalized cancer vaccine comprising tumor-derived membrane vesicles containing immunostimulatory molecules, which potentially induces an antitumor immune response and inhibits tumor growth (PMID: 32295135). |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06868433 | Phase I | Pembrolizumab + TMV vaccine TMV vaccine | TMV Vaccine Therapy Alone and with Pembrolizumab for the Treatment of Recurrent And/or Metastatic Head and Neck Squamous Cell Cancer | Recruiting | USA | 0 |
| NCT06324240 | Phase I | TMV vaccine Pembrolizumab + TMV vaccine Ipilimumab + TMV vaccine | Personalized Vaccine Immunotherapy in Combination With Checkpoint Inhibitor for Treatment of Triple Negative Breast Cancer | Not yet recruiting | USA | 0 |