Therapy Detail
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| Therapy Name | MK-1200 |
| Synonyms | |
| Therapy Description |
MK-1200 is an antibody-drug conjugate (ADC) comprising an antibody targeting CLDN18.2 linked to a DNA topoisomerase I inhibitor, which potentially induces apoptosis in CLDN18.2--expressing tumor cells (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MK-1200 | MK1200|MK 1200|SKB 315|SKB-315|SKB315 | CLDN18.2 Antibody 23 | MK-1200 is an antibody-drug conjugate (ADC) comprising an antibody targeting CLDN18.2 linked to a DNA topoisomerase I inhibitor, which potentially induces apoptosis in CLDN18.2--expressing tumor cells (NCI Drug Dictionary). |
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06242691 | Phase II | MK-1200 | Safety and Efficacy of MK-1200 in Participants With Advanced Solid Tumors | Completed | USA | ISR | AUS | 3 |
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