Therapy Detail
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| Therapy Name | Carboplatin + Docetaxel + Trastuzumab-anns |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Carboplatin | Paraplatin | CBDCA | Chemotherapy - Platinum 7 | Paraplatin (carboplatin) is a second-generation platinum compound and is activated intracellularly to form reactive platinum complexes that cross link DNA with DNA and with proteins. This induces apoptosis and inhibits cell growth (NCI Drug Dictionary). |
| Docetaxel | Taxotere | RP56976 | Antimicrotubule Agent 14 | Taxotere (docetaxel) binds to tubulin, inhibiting microtubule disassembly and preventing cell division (PMID: 32496783, PMID: 32366558). |
| Trastuzumab-anns | Kanjinti | ABP 980 | HER2 (ERBB2) Antibody 76 | Kanjinti (Trastuzumab-anns) is a Herceptin (trastuzumab) biosimilar that binds to Erbb2 (Her2), which potentially results in anti-tumor immune response against Erbb2 (Her2)-positive tumors (PMID: 31798693). Kanjinti (Trastuzumab-anns) is FDA approved for use in patients with Erbb2 (Her2) overexpressing breast, metastatic gastric or gastroesophageal junction adenocarcinoma (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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