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Therapy Name Lu-177-DOTAGA-IAC
Synonyms
Therapy Description

Lu-177-DOTAGA-IAC is a radioconjugate comprising the radionuclide Lutetium-177 conjugated to a peptidomimetic molecule that targets integrin Avb3, which potentially delivers radionuclide therapy to Avb3-expressing tumors (Journal of Nuclear Medicine June 2022, 63 (supplement 2) 2879).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Lu-177-DOTAGA-IAC Lu-177-avb3-IAC|Lutetium Lu-177-DOTAGA-IAC|HurlutinTM Lu-177 Lu-177-DOTAGA-IAC is a radioconjugate comprising the radionuclide Lutetium-177 conjugated to a peptidomimetic molecule that targets integrin Avb3, which potentially delivers radionuclide therapy to Avb3-expressing tumors (Journal of Nuclear Medicine June 2022, 63 (supplement 2) 2879).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04469127 Phase Ib/II Lu-177-DOTAGA-IAC A Phase I/II Multicenter, Open-Label Study of Lu-177-avB3-IAC, for the Treatment of Angiogenic Breast Cancer Patients. (Heroine01) Not yet recruiting 2


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