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Therapy Detail
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| Therapy Name | Anti-CD19/CD20/CD22 CAR-T Cells |
| Synonyms | |
| Therapy Description |
Anti-CD19/CD20/CD22 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, CD20, and CD22, which may induce antitumor activity (Blood (2022) 140 (Supplement 1): 7474–7475). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Anti-CD19/CD20/CD22 CAR-T Cells | CD19 Immune Cell Therapy 65 CD20 Immune Cell Therapy 13 CD22 Immune Cell Therapy 15 | Anti-CD19/CD20/CD22 CAR-T cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD19, CD20, and CD22, which may induce antitumor activity (Blood (2022) 140 (Supplement 1): 7474–7475). |
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- Case insensitive filtering will display rows if any text in any cell matches the filter term
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05418088 | Phase I | Cyclophosphamide + Fludarabine Anti-CD19/CD20/CD22 CAR-T Cells | Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies | Recruiting | USA | 0 |
| NCT06879340 | Phase I | Cyclophosphamide + Fludarabine Anti-CD19/CD20/CD22 CAR-T Cells | Evaluating the Safety and Efficacy of DuoCAR20.19.22-D95 in Adult Patients with Relapsed or Refractory B-cell Malignancies | Recruiting | USA | 0 |
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