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Therapy Name | KIND T cells |
Synonyms | |
Therapy Description |
KIND T cells are HLA-A2+ CD8+ T-lymphocytes engineered to express a T-cell receptor (TCR) targeting the histone H3.3 K27M (K28M) mutation, which potentially induce killing of tumor cells expressing HLA-A2+ and H3.3K27M (PMID: 29203539). |