Therapy Detail
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| Therapy Name | YL211 |
| Synonyms | |
| Therapy Description |
YL211 is an antibody-drug conjugate (ADC) comprising an antibody targeting MET linked to a topoisomerase 1 inhibitor, which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2024) 84 (6_Supplement): 2615). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| YL211 | YL-211|YL 211 | MET Antibody 38 | YL211 is an antibody-drug conjugate (ADC) comprising an antibody targeting MET linked to a topoisomerase 1 inhibitor, which potentially induces cell cycle arrest and apoptosis and inhibits tumor growth (Cancer Res (2024) 84 (6_Supplement): 2615). |
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06384352 | Phase I | YL211 | A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors | Recruiting | USA | CAN | AUS | 1 |
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