Therapy Detail
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| Therapy Name | SGN-35C |
| Synonyms | |
| Therapy Description |
SGN-35C is an antibody-drug conjugate (ADC) comprising an antibody targeting CD30 linked to a camptothecin-derived TOP1 inhibitor, which potentially induces cytotoxicity against tumor cells and inhibits tumor growth (Blood (2023) 142 (Supplement 1): 1440). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| SGN-35C | SGN 35C|SGN35C | SGN-35C is an antibody-drug conjugate (ADC) comprising an antibody targeting CD30 linked to a camptothecin-derived TOP1 inhibitor, which potentially induces cytotoxicity against tumor cells and inhibits tumor growth (Blood (2023) 142 (Supplement 1): 1440). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06254495 | Phase I | SGN-35C | A Safety Study of PF-08046044/SGN-35C in Adults With Advanced Cancers | Active, not recruiting | USA | ITA | GBR | FRA | ESP | DNK | 0 |
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