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Therapy Name SGN-35C
Synonyms
Therapy Description

SGN-35C is an antibody-drug conjugate (ADC) comprising an antibody targeting CD30 linked to a camptothecin-derived TOP1 inhibitor, which potentially induces cytotoxicity against tumor cells and inhibits tumor growth (Blood (2023) 142 (Supplement 1): 1440).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
SGN-35C SGN 35C|SGN35C SGN-35C is an antibody-drug conjugate (ADC) comprising an antibody targeting CD30 linked to a camptothecin-derived TOP1 inhibitor, which potentially induces cytotoxicity against tumor cells and inhibits tumor growth (Blood (2023) 142 (Supplement 1): 1440).

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06254495 Phase I SGN-35C A Safety Study of SGN-35C in Adults With Advanced Cancers Recruiting USA | ITA | DNK 0


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