Therapy Detail
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| Therapy Name | IBI3005 |
| Synonyms | |
| Therapy Description |
IBI3005 is an antibody-drug conjugate (ADC) comprising a bispecific antibody targeting EGFR and ERBB3 (HER3) linked to a camptothecin derivative, which potentially induces cell cycle arrest and apoptosis in tumor cells expressing EGFR and ERBB3 (HER3) (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| IBI3005 | IBI-3005|IBI 3005 | EGFR Antibody 73 HER3 (ERBB3) Antibody 28 | IBI3005 is an antibody-drug conjugate (ADC) comprising a bispecific antibody targeting EGFR and ERBB3 (HER3) linked to a camptothecin derivative, which potentially induces cell cycle arrest and apoptosis in tumor cells expressing EGFR and ERBB3 (HER3) (NCI Drug Dictionary). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06418061 | Phase I | IBI3005 | Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors | Recruiting | 1 |
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