Therapy Detail
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| Therapy Name | MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine |
| Synonyms | |
| Therapy Description |
MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine is a combination of two chimeric peptide vaccines comprising a promiscuous measles virus (MVF) T cell epitope fused to Erbb2 (Her2) peptides spanning amino acids 597-626 and 266-296, which potentially inhibits Erbb2 (Her2) signaling and induces antibody-dependent cellular cytotoxicity against Erbb2 (Her2)-expressing tumors (PMID: 30804020). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine | HER2 (ERBB2) Vaccine 15 | MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine is a combination of two chimeric peptide vaccines comprising a promiscuous measles virus (MVF) T cell epitope fused to Erbb2 (Her2) peptides spanning amino acids 597-626 and 266-296, which potentially inhibits Erbb2 (Her2) signaling and induces antibody-dependent cellular cytotoxicity against Erbb2 (Her2)-expressing tumors (PMID: 30804020). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06949410 | Phase I | MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine | HER2 Vaccine for Locally Advanced Breast Cancer | Recruiting | USA | 0 |
| NCT06414733 | Phase I | MVF-HER-2(597-626)/MVF-HER-2(266-296) Vaccine | Vaccine Therapy in Treating Patients With Metastatic Solid Tumors | Recruiting | USA | 0 |
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