Therapy Detail
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| Therapy Name | AGX101 |
| Synonyms | |
| Therapy Description |
AGX101 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting TM4SF1 linked to a tubulin inhibitor, which potentially inhibits growth of tumors expressing TM4SF1 (NCI Drug Dictionary, J Clin Oncol 2025 43: 16_suppl, 829). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AGX101 | AGX-101|AGX 101 | AGX101 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting TM4SF1 linked to a tubulin inhibitor, which potentially inhibits growth of tumors expressing TM4SF1 (NCI Drug Dictionary, J Clin Oncol 2025 43: 16_suppl, 829). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06440005 | Phase I | AGX101 | A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors | Recruiting | USA | 0 |
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