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Therapy Name Yttrium Y 90-DOTA-biotin
Synonyms
Therapy Description

Yttrium Y 90-DOTA-biotin is a radioconjugate comprising the radionuclide Yttrium-90 linked to the chelating agent DOTA and biotin, which may deliver targeted radiation to tumors in combination with streptavidin-conjugated antibodies, potentially resulting in reduced tumor growth (PMID: 25785845, PMID: 24371230).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
Yttrium Y 90-DOTA-biotin 90Y-DOTA-Biotin Yttrium Y 90-DOTA-biotin is a radioconjugate comprising the radionuclide Yttrium-90 linked to the chelating agent DOTA and biotin, which may deliver targeted radiation to tumors in combination with streptavidin-conjugated antibodies, potentially resulting in reduced tumor growth (PMID: 25785845, PMID: 24371230).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06390241 Phase I Yttrium Y 90-DOTA-biotin Avidination for RadionuclideTHerapy in Nonpalpable Breast Cancer (ARTHE) Recruiting ITA 0


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