Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Therapy Name | ITRI-90 |
Synonyms | |
Therapy Description |
ITRI-90 is an androgen receptor (AR) degrader containing an AR N-terminal binding region linked to an E3 ligase-binding moeity, which induces proteasomal degradation of full-length AR and ligand-binding domain truncated AR variants, potentially leading to tumor growth inhibition (PMID: 36893587). |