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Therapy Name QXL138AM
Synonyms
Therapy Description

QXL138AM is an immunocytokine comprising an anti-CD138 antibody fused to a masked IFNalpha2a that is unmasked by proteases in the tumor microenvironment, which increases interferon signaling and cytokine release and potentially inhibits growth of CD138-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
QXL138AM QXL138AM is an immunocytokine comprising an anti-CD138 antibody fused to a masked IFNalpha2a that is unmasked by proteases in the tumor microenvironment, which increases interferon signaling and cytokine release and potentially inhibits growth of CD138-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11).

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  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06582017 Phase I QXL138AM Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma Recruiting USA 0


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