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Therapy Name 177Lu-J591 + Docetaxel
Synonyms
Therapy Description

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Drug Name Trade Name Synonyms Drug Classes Drug Description
177Lu-J591 Lu 177 rosopatamab tetraxetan|Lu 177 MOAB J591|177Lu-DOTA-TLX591 PSMA Antibody 20 177Lu-J591 is a radioconjugate comprising the radionuclide lutetium-177 linked to a monoclonal antibody that targets PSMA (J591), which delivers radiation to PSMA-expressing tumor cells, potentially resulting in increased tumor cell death (PMID: 16203821).
Docetaxel Taxotere RP56976 Antimicrotubule Agent 14 Taxotere (docetaxel) binds to tubulin, inhibiting microtubule disassembly and preventing cell division (PMID: 32496783, PMID: 32366558).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT04876651 Phase III Docetaxel Enzalutamide 177Lu-J591 + Abiraterone + Prednisolone Abiraterone + Prednisone 177Lu-J591 + Abiraterone + Prednisone 177Lu-J591 + Enzalutamide Abiraterone + Prednisolone 177Lu-J591 + Docetaxel The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care Only Recruiting NZL | AUS 0


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