Therapy Detail
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| Therapy Name | Docetaxel + Niraparib and abiraterone acetate + Prednisolone |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Docetaxel | Taxotere | RP56976 | Antimicrotubule Agent 14 | Taxotere (docetaxel) binds to tubulin, inhibiting microtubule disassembly and preventing cell division (PMID: 32496783, PMID: 32366558). |
| Niraparib and abiraterone acetate | Akeega | CJNJ-67652000|CJNJ 67652000|CJNJ67652000 | Hormone - Anti-androgens 54 PARP Inhibitor (Pan) 31 | Akeega (niraparib and abiraterone acetate) is a combination of Zejula (niraparib) and Zytiga (abiraterone). Akeega (niraparib and abiraterone acetate) in combination with Adasone (prednisone) is FDA-approved for use in patients with metastatic castration-resistant prostate cancer harboring deleterious or suspected deleterious BRCA1/2 mutations (FDA.gov). |
| Prednisolone | Omnipred | Deltahydrocortisone |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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