Therapy Detail
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| Therapy Name | PF-07826390 |
| Synonyms | |
| Therapy Description |
PF-07826390 is a bispecific antibody that targets LILRB1 and ILT4 (LILRB2), which potentially results in reduced ILT4 (LILRB2)- and ILT2-dependent immune suppression and enhanced antitumor immune response (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PF-07826390 | PF 07826390|PF07826390 | LILRB2 Antibody 12 | PF-07826390 is a bispecific antibody that targets LILRB1 and ILT4 (LILRB2), which potentially results in reduced ILT4 (LILRB2)- and ILT2-dependent immune suppression and enhanced antitumor immune response (NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06546553 | Phase I | PF-07826390 PF-06801591 + PF-07826390 | A Study to Learn About How Different Amounts of the Study Medicine PF-07826390 Act in the Body of People With Cancer When Taken Alone or With Other Anti-cancer Medicines. | Terminated | USA | 0 |
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