Therapy Detail
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| Therapy Name | SGN-MesoC2 |
| Synonyms | |
| Therapy Description |
SGN-MesoC2 is an antibody-drug conjugate (ADC) comprising an anti-MSLN antibody linked to a camptothecin-based topoisomerase I inhibitor, which potentially induces cytotoxicity in MSLN-expressing tumor cells and antitumor activity (Cancer Res (2025) 85 (8_Supplement_1): 324). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| SGN-MesoC2 | SGN MesoC2|SGNMesoC2|PF08052666|PF 08052666|PF08052666|HBM9033 | MSLN Antibody 13 | SGN-MesoC2 is an antibody-drug conjugate (ADC) comprising an anti-MSLN antibody linked to a camptothecin-based topoisomerase I inhibitor, which potentially induces cytotoxicity in MSLN-expressing tumor cells and antitumor activity (Cancer Res (2025) 85 (8_Supplement_1): 324). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06466187 | Phase I | SGN-MesoC2 | A Study of SGN-MesoC2 in Advanced Solid Tumors | Recruiting | USA | CAN | 0 |
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