Therapy Detail
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| Therapy Name | Budigalimab + TTX-030 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Budigalimab | ABBV181|ABBV 181|ABBV-181 | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 | Budigalimab is a monoclonal antibody that targets PD-1 (PDCD1) and inhibits binding of the PD-L1 (CD274) ligand, potentially resulting in enhanced anti-tumor immune response (PMID: 32770720). | |
| TTX-030 | TTX030|TTX 030 | Adenosine Targeting 23 CD39 Antibody 5 | TTX-030 is a monoclonal antibody that binds to and inhibits soluble and membrane-bound ENTPD1 (CD39), resulting in decreased ATP hydrolysis, which potentially leads to activation of T-lymphocytes and anti-tumor immune response (AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 5012). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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