Therapy Detail
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| Therapy Name | M3554 |
| Synonyms | |
| Therapy Description |
M3554 is an antibody-drug conjugate (ADC) comprising an antibody targeting GD2 linked to the topoisomerase I inhibitor exatecan, which potentially induces cytotoxicity against GD2-positive cells and inhibits tumor growth (Cancer Res (2024) 84 (7_Supplement): ND08). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| M3554 | GD2 Antibody 6 | M3554 is an antibody-drug conjugate (ADC) comprising an antibody targeting GD2 linked to the topoisomerase I inhibitor exatecan, which potentially induces cytotoxicity against GD2-positive cells and inhibits tumor growth (Cancer Res (2024) 84 (7_Supplement): ND08). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06641908 | Phase I | M3554 | Anti-GD2 ADC M3554 in Advanced Solid Tumors | Recruiting | USA | GBR | FRA | CHE | BEL | 1 |
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