Therapy Detail
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| Therapy Name | BND-22 + Cetuximab |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BND-22 | BND22|BND 22|SAR444881 | BND-22 is an anti-ILT2 monoclonal antibody that blocks ILT2 from interacting with HLA-G, potentially leading to immunosuppressive effects and subsequent anti-tumor activity, including increased macrophage activity and inhibition of tumor growth (Cancer Res 2020;80(16 Suppl):Abstract nr 3266). | ||
| Cetuximab | Erbitux | IMC-C225 | EGFR Antibody 60 | Erbitux (cetuximab) is a monoclonal antibody directed against EGFR, which inhibits signal transduction and cell proliferation (PMID: 28695301). Erbitux (cetuximab) is FDA approved for use in head and neck squamous cell carcinoma and KRAS wild-type, EGFR positive colorectal cancer (FDA.gov). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|
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