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| Therapy Name | TUB-030 |
| Synonyms | |
| Therapy Description |
TUB-030 is an antibody-drug conjugate (ADC) comprising an antibody targeting TPBG (5T4) linked to the topoisomerase I inhibitor exatecan, which potentially induces cytotoxicity against TPBG (5T4)-expressing tumor cells and inhibits tumor growth (Cancer Res (2024) 84 (6_Supplement): 2623). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TUB-030 | TUB030|TUB 030 | TUB-030 is an antibody-drug conjugate (ADC) comprising an antibody targeting TPBG (5T4) linked to the topoisomerase I inhibitor exatecan, which potentially induces cytotoxicity against TPBG (5T4)-expressing tumor cells and inhibits tumor growth (Cancer Res (2024) 84 (6_Supplement): 2623). |
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06657222 | Phase Ib/II | TUB-030 | First in Human Study of TUB-030 in Patients With Advanced Solid Tumors | Recruiting | USA | CAN | 0 |
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