Therapy Detail
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| Therapy Name | JK06 |
| Synonyms | |
| Therapy Description |
JK06 is an antibody-drug conjugate (ADC) comprising a quadrivalent biparatopic antibody targeting TPBG (5T4) linked to monomethyl auristatin E, which potentially binds to TPBG (5T4) expressed on tumor and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 5447). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| JK06 | JK-06|JK 06 | JK06 is an antibody-drug conjugate (ADC) comprising a quadrivalent biparatopic antibody targeting TPBG (5T4) linked to monomethyl auristatin E, which potentially binds to TPBG (5T4) expressed on tumor and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 5447). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06667960 | Phase Ib/II | JK06 | Study of JK06 in Patients With Unresectable Locally Advanced or Metastatic Cancer | Recruiting | ESP | BEL | 0 |
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