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Therapy Name | NECVAX-NEO1 |
Synonyms | |
Therapy Description |
NECVAX-NEO1 is a personalized neoantigen cancer vaccine comprising an expression plasmid encoding patient-derived neoantigens, which may induce a cytotoxic T-lymphocyte (CTL) response against tumor cells (NCI Drug Dictionary). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
NECVAX-NEO1 | NECVAX NEO1|NECVAXNEO1 | NECVAX-NEO1 is a personalized neoantigen cancer vaccine comprising an expression plasmid encoding patient-derived neoantigens, which may induce a cytotoxic T-lymphocyte (CTL) response against tumor cells (NCI Drug Dictionary). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06631092 | Phase Ib/II | NECVAX-NEO1 | Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Neoadjuvant Triple-negative Breast Cancer | Recruiting | DEU | 0 |
NCT05354323 | Phase I | NECVAX-NEO1 | NECVAX-NEO1 in Addition to Checkpoint Inhibitor in Patients With Solid Tumors | Recruiting | LTU | 0 |
NCT06631079 | Phase Ib/II | NECVAX-NEO1 | Personalised Neoantigen-targeting Cancer Vaccine NECVAX-NEO1 in Anti-PD-1/PD-L1 Therapy in Patients With Solid Tumors | Recruiting | ESP | 0 |