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Therapy Name 161Tb-SibuDAB
Synonyms
Therapy Description

161Tb-SibuDAB is a radioligand therapy comprising the radionuclide Tb 161 linked to a PSMA-targeted ligand Sibu-DAB, which delivers radiation to PSMA-expressing tumor cells, potentially resulting in inhibition of tumor growth (PMID: 37442604).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
161Tb-SibuDAB 161Tb SibuDAB|[161Tb}-SibuDAB|[161Tb}Tb-SibuDAB 161Tb-SibuDAB is a radioligand therapy comprising the radionuclide Tb 161 linked to a PSMA-targeted ligand Sibu-DAB, which delivers radiation to PSMA-expressing tumor cells, potentially resulting in inhibition of tumor growth (PMID: 37442604).

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT06343038 Phase I Lutetium-177 PSMA-I&T 161Tb-SibuDAB Targeted Radionuclide Therapy in Metastatic Prostate Cancer Using a New PSMA Ligand Radiolabelled With Terbium-161 (161Tb-SibuDAB) - Dose Identification/Escalation Phase Ia/b Study (PROGNOSTICS) Recruiting CHE 0


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