Therapy Detail
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| Therapy Name | PTX-912 |
| Synonyms | |
| Therapy Description |
PTX-912 is a fusion protein comprising an anti-PDCD1 (PD1) monoclonal antibody linked to a conditionally masked IL-2, which potentially enhances antitumor immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer 2024;12). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PTX-912 | PTX 912|PTX912 | PD-L1/PD-1 antibody 133 | PTX-912 is a fusion protein comprising an anti-PDCD1 (PD1) monoclonal antibody linked to a conditionally masked IL-2, which potentially enhances antitumor immune response and inhibits tumor growth (Journal for ImmunoTherapy of Cancer 2024;12). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06190886 | Phase I | PTX-912 | A First-in-human (FIH), Phase I Study of PTX-912 in Patients with Locally Advanced/Metastatic Solid Tumors | Recruiting | USA | 0 |
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