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Therapy Name | Capecitabine + Tetrathiomolybdate |
Synonyms | |
Therapy Description | |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
Capecitabine | Xeloda | R340 | Chemotherapy - Antimetabolite 14 | Xeloda (capecitabine) is an antimetabolite that when activated to 5-FU ultimately inhibits DNA synthesis and cell division (NCI Drug Dictionary). |
Tetrathiomolybdate | CCRIS 9412|ATN-224 | Tetrathiomolybdate depletes systemic copper, thereby inhibiting cuproenzymes and leading to antitumor effects (PMID: 26160923, PMID: 32005716). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06134375 | Phase Ib/II | Capecitabine Capecitabine + Tetrathiomolybdate Capecitabine + Pembrolizumab + Tetrathiomolybdate Capecitabine + Pembrolizumab | A Study of Tetrathiomolybdate (TM) Plus Capecitabine | Recruiting | USA | 0 |