Therapy Detail
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| Therapy Name | ADRX-0405 |
| Synonyms | |
| Therapy Description |
ADRX-0405 is an antibody-drug conjugate (ADC) comprising an antibody targeting STEAP1 linked to a topoisomerase I inhibitor, which potentially induces cytotoxicity in STEAP1-expressing tumor cells and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 1159). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ADRX-0405 | ADRX 0405|ADRX0405 | ADRX-0405 is an antibody-drug conjugate (ADC) comprising an antibody targeting STEAP1 linked to a topoisomerase I inhibitor, which potentially induces cytotoxicity in STEAP1-expressing tumor cells and inhibits tumor growth (Cancer Res (2025) 85 (8_Supplement_1): 1159). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06710379 | Phase I | ADRX-0405 | A Study of ADRX-0405 in Subjects with Select Advanced Solid Tumors | Recruiting | USA | 0 |
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