Therapy Detail
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| Therapy Name | 177Lu-EVS459 |
| Synonyms | |
| Therapy Description |
177Lu-EVS459 is a radioconjugate comprising the radionuclide Lutetium-177 linked to EVS459, a FOLR1-targeting ligand, which delivers radiation to FOLR1-expressing tumor cells, potentially resulting in tumor cell death (NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 177Lu-EVS459 | [177Lu]Lu-EVS459|Lutetium Lu 177 EVS459 | 177Lu-EVS459 is a radioconjugate comprising the radionuclide Lutetium-177 linked to EVS459, a FOLR1-targeting ligand, which delivers radiation to FOLR1-expressing tumor cells, potentially resulting in tumor cell death (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06376253 | Phase I | 177Lu-EVS459 | A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers | Recruiting | ISR | 0 |
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