Therapy Detail
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| Therapy Name | CGT4859 |
| Synonyms | |
| Therapy Description |
CGT4859 is a selective reversible inhibitor of FGFR2 and FGFR3, with activity against mutant FGFR2, which potentially reduces proliferation of tumor cells overexpressing FGFR2 or FGFR3 (Cancer Res (2025) 85 (8_Supplement_1): 4729, NCI Drug Dictionary). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CGT4859 | CGT-4859|CGT 4859 | FGFR2 Inhibitor 24 FGFR3 Inhibitor 21 | CGT4859 is a selective reversible inhibitor of FGFR2 and FGFR3, with activity against mutant FGFR2, which potentially reduces proliferation of tumor cells overexpressing FGFR2 or FGFR3 (Cancer Res (2025) 85 (8_Supplement_1): 4729, NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06777316 | Phase Ib/II | CGT4859 | A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors | Recruiting | USA | CAN | 0 |
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