Therapy Detail
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| Therapy Name | Paclitaxel + Telmisartan |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Paclitaxel | Taxol | 7-Epipaclitaxel | Antimicrotubule Agent 14 BCL2 Family Inhibitor 6 | Taxol (paclitaxel) binds to tubulin to inhibit microtubule disassembly, which results in decreased cell division, and also binds to the anti-apoptotic factor Bcl-2, promoting apoptosis (NCI Drug Dictionary). |
| Telmisartan | BIBR 277|Micardis | Telmisartan is a AT1R antagonist that also acts as a PPARG agonist to inhibit IL-6 expression, potentially resulting in decreased tumor cell proliferation (PMID: 39032472). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06815497 | Phase II | Docetaxel + Telmisartan Paclitaxel + Telmisartan Nab-paclitaxel + Telmisartan Doxorubicin + Telmisartan Pegylated liposomal doxorubicin + Telmisartan | Telmisartan in Combination with Cytotoxic Regimens in Platinum-Resistant Ovarian Cancer | Not yet recruiting | USA | 0 |
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