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Therapy Name | AZD9793 |
Synonyms | |
Therapy Description |
AZD9793 is a CD8-guided T-cell engager comprising a monoclonal trispecific antibody targeting GPC3, TCR, and CD8 co-receptor, which potentially induces cytolysis of GPC3-expressing tumor cells (Journal for ImmunoTherapy of Cancer 2024;12). |
Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
---|---|---|---|---|
AZD9793 | AZD-9793|AZD 9793 | GPC3 Antibody 6 | AZD9793 is a CD8-guided T-cell engager comprising a monoclonal trispecific antibody targeting GPC3, TCR, and CD8 co-receptor, which potentially induces cytolysis of GPC3-expressing tumor cells (Journal for ImmunoTherapy of Cancer 2024;12). |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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NCT06795022 | Phase Ib/II | AZD9793 | First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours (RHEA-1) | Not yet recruiting | USA | 0 |