Therapy Detail
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| Therapy Name | AZD9793 |
| Synonyms | |
| Therapy Description |
AZD9793 is a CD8-guided T-cell engager comprising a monoclonal trispecific antibody targeting GPC3, TCR, and CD8 co-receptor, which potentially induces cytolysis of GPC3-expressing tumor cells (Journal for ImmunoTherapy of Cancer 2024;12). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| AZD9793 | AZD-9793|AZD 9793 | GPC3 Antibody 7 | AZD9793 is a CD8-guided T-cell engager comprising a monoclonal trispecific antibody targeting GPC3, TCR, and CD8 co-receptor, which potentially induces cytolysis of GPC3-expressing tumor cells (Journal for ImmunoTherapy of Cancer 2024;12). |
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06795022 | Phase Ib/II | AZD9793 | First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours (RHEA-1) | Recruiting | USA | ESP | 5 |
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