Therapy Detail
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| Therapy Name | DM005 |
| Synonyms | |
| Therapy Description |
DM005 is an antibody-drug conjugate (ADC) comprising a bispecific antibody targeting EGFR and MET linked to monomethyl auristatin E (MMAE), which may have antitumor activity against EGFR and MET-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DM005 | DM 005|DM-005 | EGFR Antibody 63 MET Antibody 36 | DM005 is an antibody-drug conjugate (ADC) comprising a bispecific antibody targeting EGFR and MET linked to monomethyl auristatin E (MMAE), which may have antitumor activity against EGFR and MET-expressing tumors (Journal for ImmunoTherapy of Cancer 2023;11). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06515990 | Phase I | DM005 | A Study of DM005 in Patients With Advanced Solid Tumors | Recruiting | AUS | 0 |
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