Therapy Detail
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| Therapy Name | BHV-1530 |
| Synonyms | |
| Therapy Description |
BHV-1530 (AMB302) is an antibody-drug conjugate (ADC) comprising an FGFR3 antibody linked to a topoisomerase I inhibitor with ligase-dependent conjugation, which potentially inhibits growth of tumors with FGFR fusions or overexpression (Cancer Res (2023) 83 (7_Supplement): 2634). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BHV-1530 | BHV1530|BHV 1530AMB302|AMB-302|AMB 302|GR 1017|GR-1017|GR1017 | FGFR3 Antibody 5 | BHV-1530 (AMB302) is an antibody-drug conjugate (ADC) comprising an FGFR3 antibody linked to a topoisomerase I inhibitor with ligase-dependent conjugation, which potentially inhibits growth of tumors with FGFR fusions or overexpression (Cancer Res (2023) 83 (7_Supplement): 2634). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06874335 | Phase I | BHV-1530 | A Phase 1 Study of BHV-1530 (AMB302) in Advanced Solid Tumors | Recruiting | USA | 0 |
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