Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Therapy Name | Anti-CD83 CAR-T cells |
Synonyms | |
Therapy Description |
Anti-CD83 CAR-T cells are T-cells that have been engineered to express a chimeric antigen receptor (CAR) that targets CD83 and contains a CD8 hinge and 4-1BB costimulatory and CD3-zeta activation domains, which potentially leads to enhanced anti-tumor immune response against CD83-expressing tumor cells (PMID: 36622700, PMID: 32437331). |