Therapy Detail
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| Therapy Name | DOC1021 + Temozolomide |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DOC1021 | DOC-1021|DOC 1021 | DOC1021 is a cancer vaccine comprising autologous dendritic cells loaded with autologous tumor lysate and amplified mRNA, which potentially enhances antitumor immune response (Journal for ImmunoTherapy of Cancer 2024;12). | ||
| Temozolomide | Temodar | Methazolastone|TMZ | Chemotherapy - Alkylating 18 | Temodar (temozolomide) is a dacarbazine analog and cytotoxic alkylating agent (NCI Drug Dictionary). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06805305 | Phase II | Temozolomide DOC1021 + Temozolomide | DOC1021 Dendritic Cell Immunotherapy for Treatment of Newly Diagnosed Adult Glioblastoma (GBM) | Recruiting | USA | 0 |
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