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Therapy Name | TGFbetaR2KO/IL13Ralpha2 CAR-T cells |
Synonyms | |
Therapy Description |
TGFbetaR2KO/IL13Ralpha2 CAR-T cells are autologous T-lymphocytes engineered with knockout of TGFbRII expression and to express a chimeric antigen receptor (CAR) targeting IL13Ra2, which potentially induce toxicity in IL13Ra2-expressing tumor cells (NCI Thesaurus). |