Therapy Detail
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| Therapy Name | CAR20(NAP) T-cells |
| Synonyms | |
| Therapy Description |
CAR20(NAP) T-cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD20 and to secrete the Helicobacter pylori-derived neutrophil activating protein (NAP), which potentially induce tumor cell cytotoxicity and inhibit tumor growth (PMID: 40650770). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| CAR20(NAP) T-cells | CAR20-NAP T-cells|CAR20(NAP)-T cells|ELC-301|ELC301|ELC 301 | CD20 Immune Cell Therapy 14 | CAR20(NAP) T-cells are T-lymphocytes engineered to express a chimeric antigen receptor (CAR) targeting CD20 and to secrete the Helicobacter pylori-derived neutrophil activating protein (NAP), which potentially induce tumor cell cytotoxicity and inhibit tumor growth (PMID: 40650770). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06002659 | Phase Ib/II | Cyclophosphamide + Fludarabine CAR20(NAP) T-cells | CAR20(NAP)-T Therapy for B Cell Lymphoma (CARMA-01 Study) (CARMA-01) | Recruiting | SWE | 0 |
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