Therapy Detail
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| Therapy Name | DZD6008 |
| Synonyms | |
| Therapy Description |
DZD6008 is a brain-penetrant 4th generation EGFR inhibitor, with activity against EGFR L858R, exon 19 deletions, T790M, and C797 mutations, which potentially induces antitumor activity (J Clin Oncol 2025 43: 16_suppl, 8616). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| DZD6008 | DZD 6008|DZD-6008 | EGFR Inhibitor 4th gen 19 | DZD6008 is a brain-penetrant 4th generation EGFR inhibitor, with activity against EGFR L858R, exon 19 deletions, T790M, and C797 mutations, which potentially induces antitumor activity (J Clin Oncol 2025 43: 16_suppl, 8616). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06905197 | Phase I | DZD6008 | A Multinational Study Assessing an Oral EGFR Inhibitor, DZD6008 in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN1) | Recruiting | USA | AUS | 0 |
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