Therapy Detail
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| Therapy Name | TYRA-430 |
| Synonyms | |
| Therapy Description |
TYRA-430 is an Fgfr3/4 inhibitor, which potentially inhibits tumor growth (J Clin Oncol 2025 43: 4_suppl, 583). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| TYRA-430 | TYRA 430|TYRA430 | FGFR3 Inhibitor 21 FGFR4 Inhibitor 10 | TYRA-430 is an Fgfr3/4 inhibitor, which potentially inhibits tumor growth (J Clin Oncol 2025 43: 4_suppl, 583). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06915753 | Phase I | TYRA-430 | Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations (SURF431) | Recruiting | USA | CAN | 2 |
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