Therapy Detail
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| Therapy Name | ABBV-637 + ERAS-801 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ABBV-637 | ABBV637|ABBV 637 | EGFR Antibody 72 | ABBV-637 is an antibody-drug conjugate (ADC) comprising an antibody targeting EGFR linked to a BCL-XL inhibitor, which potentially induces antitumor activity (Ann Oncol (2023) 34 (suppl_2): S759). | |
| ERAS-801 | ERAS801|ERAS 801 | EGFR Inhibitor (Pan) 63 | ERAS-801 is an EGFR inhibitor with improved blood-brain barrier penetrating ability, potentially leading to inhibition of growth of EGFR-overexpressing tumor cells (NCI Drug Dictionary). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
- Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06934889 | Phase I | ABBV-637 + ERAS-801 ABBV-637 + Temozolomide ERAS-801 + Mirzotamab clezutoclax Mirzotamab clezutoclax + Temozolomide | Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma | Recruiting | USA | 0 |
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