Therapy Detail
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| Therapy Name | 177Lu-DTPA-SC16 |
| Synonyms | |
| Therapy Description |
177Lu-DTPA-SC16 is a radioconjugate comprising a monoclonal antibody that targets DLL3 linked to the radionuclide lutetium-177, which delivers radiation to DLL3-expressing tumor cells, potentially inhibiting tumor growth (PMID: 35759660). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| 177Lu-DTPA-SC16 | 177Lu-DTPASC16|177Lu-DTPA-SC16.56|Lutetium 177-DTPA-SC16 | DLL3 Antibody 10 | 177Lu-DTPA-SC16 is a radioconjugate comprising a monoclonal antibody that targets DLL3 linked to the radionuclide lutetium-177, which delivers radiation to DLL3-expressing tumor cells, potentially inhibiting tumor growth (PMID: 35759660). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06941480 | Phase I | 177Lu-DTPA-SC16 | A Study of 177Lu-DTPA-SC16.56 in People With Neuroendocrine Carcinomas of the Lung and Prostate | Not yet recruiting | USA | 0 |
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