Therapy Detail
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| Therapy Name | ADCE-D01 |
| Synonyms | |
| Therapy Description |
ADCE-D01 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting uPARAP (MRC2) linked to P-1021, which potentially induces DNA damage and tumor cell death (Cancer Res (2025) 85 (8_Supplement_1): 4784). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| ADCE-D01 | ADCED01|ADCE D01 | ADCE-D01 is an antibody-drug conjugate (ADC) comprising a monoclonal antibody targeting uPARAP (MRC2) linked to P-1021, which potentially induces DNA damage and tumor cell death (Cancer Res (2025) 85 (8_Supplement_1): 4784). |
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06797999 | Phase Ib/II | ADCE-D01 | First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma (ADCElerate1) | Recruiting | USA | GBR | FRA | DEU | BEL | 0 |
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